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CaMK1 plays multiple roles in neuronal development and plasticity and is required for the regulation of axonal outgrowth and growth cone morphology, dendritic branching, and formation of dendritic spines and synapses [94,95,96,97,98]
In patients with progressive myoclonus epilepsy, a GSTT1 -null genotype has been associated with increased risk of developing the disease where it might contribute to enhanced susceptibility to oxidative stress 60
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Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition